[关键词]
[摘要]
当归-川芎是临床方剂常见药对,二药配伍具有养血补血、活血化瘀功效。现代研究发现,当归-川芎药对富含生物碱、有机酸、挥发油等活性成分,具有抗炎镇痛、抗氧化、补血活血、神经保护等作用,临床应用广泛,可用于治疗各类妇科疾病、心脑血管疾病、血液系统疾病等。结合国内外文献,从化学成分、药理作用、临床应用角度出发,综述近年来当归-川芎的研究现状,以期为该药对的科学应用及新药研发提供理论依据。
[Key word]
[Abstract]
Danggui (Angelicae Sinensis Radix) and Chuanxiong (Chuanxiong Rhizoma) (RAS-CR) is a common drug pair in clinical prescriptions. The compatibility of the two drugs has the effects of nourishing blood and tonifying blood, promoting blood circulation and removing blood stasis. Modern researchs have found that RAS-CR is rich in active ingredients such as alkaloids, organic acids, and volatile oils, with anti-inflammatory, analgesia, anti-oxidant, blood replenishment, neuroprotection and other effects. It is widely used in clinical applications and can be used to treat various gynecological diseases, cardiovascular and cerebrovascular diseases, and blood system diseases, etc. Based on the literature at home and abroad, this paper reviews the research status of RAS-CR in recent years from the perspective of chemical composition, pharmacological effects and clinical applications, in order to provide a theoretical basis for the scientific application of the drug pair and the research and development of new drugs.
[中图分类号]
[基金项目]
科技型中小企业创新能力提升工程(TSGC1359);中央引导地方科技发展资金项目(YDZX2021050)