槟榔Arecae Semen是我国传统医学常用的中药材，药用历史悠久，具有杀虫、消积、行气、利水、截疟等功效。近年来，关于食用槟榔诱发口腔癌的负面报道较多，关注焦点主要集中于食用方面，忽略了药用价值。海南省是我国槟榔的主产区，以食用为主，严重制约了槟榔的使用和发展空间，不利于海南槟榔产业的可持续发展。通过梳理汉代以来中医药本草典籍中关于槟榔功效记载的历史脉络，归纳总结历代医家对其功效认识及在临床上的应用，同时整理了现阶段槟榔药用的概况及安全性的研究报道，为槟榔药用的开发利用提供参考。

Binlang (Arecae Semen), a traditional Chinese medicinal material with a long history of use in our country Chinese traditional medicine, which has the functions of expelling parasites, promoting digestion, promoting qi, draining water-dampness and stopping malaria. However, there have been numerous negative reports in recent years linking oral cancer to the consumption of Arecae Semen. While the focus has primarily been on its edible properties, the medicinal value of Arecae Semen has been overlooked. Hainan Province is the main producing area for Arecae Semen in China, which is mainly edible, which seriously restricts the use and development space of Arecae Semen, and is not conducive to the sustainable development of Arecae Semen industry in Hainan. Through sorting out the historical contexts of efficacy of Arecae Semen found in classics of traditional Chinese medicine dating back to the Han dynasty, this paper summarizes the understanding of its efficacy throughout past dynasties as well as its clinical application and sorts out the current state of medicinal use and existing research reports on its safety. The aim is to provide valuable insights for the development and utilization of Arecae Semen medicine.

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海南省重点研发计划项目（ZDYF2023SHFZ141，ZDYF2022XDNY162）；中国医学科学院医学与健康科技创新工程（2021-I2M-1-032）