目的 探析21世纪以来全球中医药学者在枸杞科学研究领域的跨地域多维协作态势，梳理研究热点、前沿动态及研究主题的地域分布，为今后的研究提供参考。方法 收集Web of Science、PubMed、中国知网（CNKI）、维普（VIP）和万方（Wanfang）数据库2000年1月1日—2022年6月31日与枸杞相关的文献，通过文献计量软件COOC9.9对其进行整合，利用VOSviewer1.6.18软件进行可视化分析，构建枸杞的知识图谱。结果 经过筛选最终纳入国际文献206篇，国内文献23 843篇，发文量最多的是宁夏农林科学院枸杞研究所曹有龙；研究机构发文量最多的是中国科学院和宁夏大学；高载文量期刊分别是Asian Journal of Chemistry和《宁夏农林科技》。我国在本研究领域处于核心地位，与美国、瑞士合作较为频繁。结论 基于数据融合与驱动可视化技术，从时间和地域的视角出发，分析枸杞研究趋势并进行价值发现研究，为枸杞产业高质量发展进程中新经济增长点的剖析、发展战略的规划与实施提供数据可视化依据。

Objective To explore the cross regional and multi-dimensional collaboration trend of global traditional Chinese medicine scholars in the field of Gouqi (Lycium chinense Mill.) scientific research since the 21st century, sort out the regional distribution of research hotspots, cutting-edge trends, and researching topics, provideing reference for future research. Method The literature related to L. chinense from the Web of Science, Pubmed, CNKI, VIP and Wanfang databases was collected from January 1, 2000 to June 31, 2022. It was integrated by bibliometric software COOC9.9, and visualized and analyzed by using VOSviewer 1.6.18 software to construct a knowledge graph of L. chinense. Result After screening, 206 international literature were selected, and 23843 domestic literature were included in the standard. Cao Youlong who from the Chinese wolfberry Research Institute of Ningxia Academy of Agriculture and Forestry Sciences had the highest number of publications; The Chinese Academy of Sciences and Ningxia University have the largest number of papers issued by research institutions; The high-volume journals are Asian Journal of Chemistry and Ningxia Agriculture and Forestry Science and Technology respectively; China is at the core of this research field and has frequent cooperation with the United States and Switzerland. Conclusion Based on data fusion and driven visualization, analyze the research trend of L. chinense and conduct value discovery research from a temporal and geographical perspective. So as to provide data visualization basis for the analysis of new economic growth points, planning and implementation of development strategies in the high-quality development process of L. chinense industry.

中国工程院战略研究与咨询项目（GS2021ZDA06）；道地药材生态种植及质量保障项目［国中医药科技（2020）153号］；财政部和农业农村部：国家现代农业产业技术体系资助项目（CARS-21）