基于物理化学方法的“中药溶液环境”学说，借助物理化学宏观的“热力学方法”与微观的“统计力学”间的相互沟通，对中药制药过程的宏观现象给以深刻的说明，而得以破析其工程原理。以“中药热法及膜蒸馏浓缩过程瞬时能耗精准计算”“中药反渗透膜浓缩过程的起泡行为及其机制”等若干中药制药浓缩过程难题为例，通过建立“白利度”等“中药溶液环境”表征参数的相关性模型；对中药浓缩过程中的“起泡行为”进行微观、动态表征，并探索发泡性、泡沫结构和稳定性与“溶液环境”物理化学特征参数的相关性，为消除中草药提取物加工过程中起泡的不利影响提供新策略。将物理化学基本原理引入中药制药过程，从药物组分在各单元操作中的空间移动等宏观和微观变化角度，基于该过程的热力学、动力学规律，认识中药制药过程的控制技术、方法、标准和规范，从“过程工程原理”的科学本质认识、创新现有的中药制药理论与技术体系，是传统中药制药产业走向高新技术化的必由之路。

The macroscopic phenomenon in the process of traditional Chinese medicine (TCM) production can be deciphered by communication between the macroscopic “thermodynamic method” and the microscopic “statistical mechanics” of physical chemistry, under the theory of “Chinese medicine solution environment” to disprove its engineering principles. Taking “accurate calculation of instantaneous energy consumption of TCM in thermal method and membrane distillation concentration process” and “foaming behavior and mechanism of reverse osmosis membrane concentration process of TCM” as examples, the correlation model of characteristic parameters of “Chinese medicine solution environment” such as “Brix degree” was established. The “foaming behavior” in the process of Chinese herbal medicine concentration was characterized microscopically and dynamically, and the correlation between foaming property, foam structure and stability and the physicochemical characteristics of the “solution environment” was explored to provide a new strategy for eliminating the adverse effects of foaming during the processing of Chinese herbal medicine extract. Introducing the basic principles of physics and chemistry into the TCM pharmaceutical process, understanding the control technology, methods, standards and norms of the TCM pharmaceutical process from the perspective of macro and micro changes such as the spatial movement of drug components in each unit operation based on the laws of thermodynamics and dynamics of the process, and understanding and innovating the existing TCM pharmaceutical theory and technology system from the scientific essence of “process engineering principle”, which is the only way for the traditional Chinese medicine pharmaceutical industry to become high-tech.