[关键词]
[摘要]
痛风是单钠尿酸盐沉积在关节所致的晶体相关性关节病,与嘌呤代谢紊乱和(或)尿酸排泄障碍所致的高尿酸血症直接相关,除关节损害,还可伴发肾脏病变及其他代谢综合征的表现,临床常见的代谢性风湿病。近年来关于中医药治疗痛风的研究越来越多,包括中药单体、单味药、中药复方和中医外治法,其具有疗效显著且无明显不良反应的优势。通过对痛风的病因病机、中医药治疗的基础研究和临床研究等方面进行全面综述,为临床治疗提供理论依据。
[Key word]
[Abstract]
Gouty is a crystal-related arthropathy caused by monosodium urate deposition in the joints, which is directly related to hyperuricemia caused by purine metabolism disorders and (or) uric acid excretion disorders. In addition to joint damage, but also accompanied by renal lesions and other metabolic syndrome manifestations. It is a common metabolic rheumatic disease. In recent years, there are more and more researches on the treatment of gouty, including Chinese medicine monomer, single medicine, Chinese medicine compound, and traditional Chinese medicine (TCM) external treatment. It has unique advantages with remarkable curative effect and no obvious toxic side effects. Therefore, this paper makes a comprehensive review on the etiology and pathogenesis of gouty, basic research and clinical research of TCM treatment, in order to provide theoretical basis for clinical treatment.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(82074377);国家自然科学基金资助项目(81673927)