目的 观察痹祺胶囊联合“烧山火”手法深刺颈夹脊穴治疗气滞血瘀型颈椎病的临床疗效和安全性。方法 选取气滞血瘀型颈椎病患者78例，采用随机数字表法将其分为2组，每组39例。两组患者均给予“烧山火”针刺手法深刺颈夹脊穴，1次/d，连续治疗2周；对照组采用注射用氯诺昔康静脉滴注，8 mg/次，1次/d；观察组采用痹祺胶囊口服，4粒/次，2次/d；两组患者均连续治疗2周。观察两组患者临床疗效，比较简化麦吉尔疼痛问卷（simplified McGill score chart for paining questionnaire，SF-MPQ）评分及颈椎病评估量表（assessment scale for cervical spondylosis，ASCS）评分的变化，评价治疗期间药物的安全性。结果 治疗后，观察组总有效率为92.11%，显著高于对照组的80.56%，两组比较差异显著（P＜0.05）。治疗后，两组SF-MPQ总评分及亚量表（PRI、VAS、PPI）评分较治疗前均显著降低（P＜0.05），且治疗后观察组显著低于对照组（P＜0.05）。治疗后，两组ASCS总评分及亚量表（自觉症状、临床检查、日常生活动作）评分较治疗前均显著升高（P＜0.05），且治疗后观察组显著高于对照组（P＜0.05）。1个月后随访，观察组SF-MPQ、ASCS评分仍优于对照组，差异具有统计学意义（P＜0.05）。除1例晕针，未出现药物相关不良反应。结论 痹祺胶囊联合“烧山火”针刺手法深刺颈夹脊穴治疗气滞血瘀型颈椎病疗效显著，能有效降低患者疼痛程度，改善颈部活动功能，提高患者的生活质量，安全性良好，作用更加持久稳定。

Objective To observe the clinical effect and safety evaluation of Biqi Capsules (痹祺胶囊) combined with "burning mountain fire" acupuncture manipulation to deeply prick the cervical Jiaji acupoints in the treatment of cervical spondylosis of qi stagnation and blood stasis. Methods A total of 78 cases of cervical spondylosis with qi stagnation and blood stasis were selected and randomly divided into two groups, with 39 cases in each group. Patients in both groups were given deep prick at cervical Jiaji acupoints by “burning mountain fire” acupuncture, once a day for two weeks. The control group was treated with lornoxicam for injection by intravenous drip, 8 mg/time, once a day; The observation group took Biqi Capsules orally, 4 capsules/time, two times a day; Patients in both groups were treated continuously for two weeks. The clinical efficacy, simplified McGill score chart for paining questionnaire (SF-MPQ) score and the changes of the assessment scale for cervical spondylosis (ASCS) were compared between the two groups to evaluate the safety of drugs during treatment. Results After treatment, the total effective rate of the observation group was 92.11%, which was significantly higher than that of the control group (80.56%). There was significant difference between the two groups (P < 0.05). After treatment, the total score of SF-MPQ and the scores of subscale (PRI, VAS, PPI) in the two groups were significantly lower than those before treatment (P < 0.05), and those in the observation group after treatment were significantly lower than those in the control group (P < 0.05). After treatment, the total score of ASCS and the scores of subscale (conscious symptoms, clinical examination, daily life action) in the two groups were significantly higher than those before treatment (P < 0.05), and the scores in the observation group after treatment were significantly higher than those in the control group (P < 0.05). The follow-up visit after one month showed that the SF-MPQ and ASCS scores of the observation group were still superior to those of the control group, and the differences were statistically significant (P < 0.05). Except for one case of needle fainting, there were no drug-related adverse reactions. Conclusion Biqi Capsules combined with “burning mountain fire” acupuncture at cervical Jiaji acupoints is effective in the treatment of cervical spondylosis with qi stagnation and blood stasis type, which can effectively reduce the degree of pain in patients, improve the neck movement function, and improve the quality of life of patient, with good safety and more durable and stable effect.

R285.64

安徽省教育厅科学研究重点项目（2022AH050469）；安徽省中医药传承创新科研项目（2022CCZC02）；安徽中医药大学临床科研项目（2021efylc31）；长三角名中医工作室（詹红生工作室）［皖中医药发展秘（2023）16号］；安徽省“十四五”省级中医优势特色专科[皖中医药服务秘（2021）71号]；安徽省科技攻关项目（1704a0802168）