[关键词]
[摘要]
目的 基于CiteSpace全面、科学地梳理黄精多糖研究领域的发展脉络和研究趋势、研究热点及前沿,并进一步分析其薄弱环节,为未来科学研究、产业发展布局等提供借鉴。方法 利用Web of Science核心合集数据库和中国知网(CNKI)数据库检索2000—2023年发表的与黄精多糖类物质研究相关文献,使用CiteSpace对发文量、共现网络和关键词进行可视化分析,并结合图谱内容解读其涵义。结果 中、英文文献总体呈现出逐年增长的趋势,段宝忠和Huang Luqi、西北农林科技大学和安徽中医药大学分别是中、英文文献发文量最高的作者和机构。黄精多糖药食同源价值发掘、九蒸九制、抗糖尿病研究、肠道微生物群研究、转录组测序分析可能是未来几年的研究热点。提取、炮制及质量控制的标准化方法且药理机制的研究不够深入,临床和商业应用有限,畜牧与动物医学领域研究相对缺乏是目前黄精多糖研究的主要薄弱环节。结论 广大科研工作者未来应致力于转录组测序分析生物合成途径及筛选差异基因,在临床实践中深入探究黄精多糖的药理作用及其临床应用,开展黄精多糖在畜牧与动物医学领域的研究,着力研发和推广黄精多糖新型功能性食品和医药产品。
[Key word]
[Abstract]
Objective Based on CiteSpace to sort out the development and research trends comprehensively and scientifically, research hotspots, and frontiers in the field of polysaccharide from Huangjing (Polygonati Rhizoma), and further analyze its weaknesses, so as to provide a reference for future scientific research and industrial development layout, etc. Methods The Web of Science core collection database and CNKI database were used to retrieve the literature related to the research on the Polygonati Rhizoma polysaccharide from 2000 to 2023, and CiteSpace was used to visualize the number of articles, co-occurrence networks, and keywords, and to interpret their meanings in the context of the graphical content. Results Both Chinese and English literature showed an overall trend of year-on-year growth, with Duan Baozhong and Huang Luqi, Northwest Agriculture and Forestry University of Science and Technology, and Anhui University of Traditional Chinese Medicine as the authors and institutions with the highest number of articles published in Chinese and English, respectively. The discovery of the medicine and food homology value, the nine-steaming and nine-making process, the anti-diabetic study, the study of the intestinal microbiota, and the transcriptome sequencing analysis may be the hot spots of research in the coming years. The lack of standardized methods for extraction, preparation, and quality control, the lack of in-depth research on pharmacological mechanisms, the limited clinical and commercial applications, and the relative lack of research in animal husbandry and animal medicine are the main weaknesses of the current research on Polygonati Rhizoma polysaccharide. Conclusion In the future, researchers should focus on transcriptome sequencing to analyze the biosynthetic pathway and its related structural gene functions, explore the pharmacological effects of Polygonati Rhizoma polysaccharide and its clinical applications in clinical practice, conduct research on Polygonati Rhizoma polysaccharide in animal husbandry and animal medicine, and invest in the development and promotion of new functional food and pharmaceutical products of Polygonati Rhizoma polysaccharide.
[中图分类号]
R28
[基金项目]
湖南省自然科学基金项目(2021JJ30514);湖南省中医药管理局项目(2021073);湖南省中医药管理局项目(2021204);湖南省研究生创新项目(CX20230829);长沙市自然科学基金项目(kq2208191)