山楂Crataegus pinnatifida属蔷薇科植物，其果实、叶、种子、根等均具有极高的价值，在医药、食品、化工等领域均有较广泛的应用。山楂不同部位的药用功效主要用于治疗心脑血管疾病、代谢性疾病、细菌感染等。随着研究逐步深入，现已有多种相关药品上市，并在临床上得到广泛使用。通过对山楂不同入药部位进行分类整理，按药理作用分别对其上市药品的临床应用、基础研究及质量研究等进行综述，探讨山楂在开发大健康产品方面的优势，为山楂的综合利用与开发提供参考。

Shanzha (Crataegi Fructus) is a plant belongs to the Rosaceae family. Its fruits, leaves, seeds, and roots all have high value and are widely used in the fields of medicine, food, and chemical industry. The medicinal properties of different parts of Crataegi Fructus are mainly focused on cardiovascular and cerebrovascular diseases, metabolic disorders, and bacterial infections. With in-depth research, multiple related drugs have been introduced to the market and widely used in clinical practice. By organizing and classifying the different medicinal parts, this study provides a review of the clinical applications, basic research, and quality studies of the marketed drugs based on their pharmacological effects. Furthermore, it explores the advantages of Crataegi Fructus in developing products for overall health, providing a reference for the comprehensive utilization and development of Crataegi Fructus.

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广州市科技计划项目珠江科技新星专项（201610010113）；国家药品监督管理局药品快速检验技术重点实验室开放课题（KF2022002，KF2022006）