目的 基于Heracles NEO超快速气相电子鼻对枳壳Aurantii Fructus饮片麸炒前后气味差异标志物进行快速识别研究，拟建立一种基于气味的有效快速识别生、麸炒枳壳饮片的方法。方法 通过建立生、麸炒枳壳饮片Heracles NEO超快速气相电子鼻检测方法，结合Arochembase数据库，采用主成分析、判别因子分析方法对生、麸炒枳壳饮片气味色谱峰进行数据处理和分析。结果 建立了生、麸炒枳壳饮片超快速气相电子鼻分析方法，通过对生、麸炒枳壳饮片气味指纹图谱分析，匹配出11个气味特征成分，推测D-柠檬烯、β-月桂烯、γ-松油烯为生、麸炒枳壳饮片气味差异标志物。结论 Heracles NEO超快速气相电子鼻可较好地快速识别生、麸炒枳壳饮片气味特征成分，可应用于饮片生产过程的质量在线监测，为饮片不同炮制品的快速识别及质量控制提供新思路和新方法。

Objective Based on Heracles NEO ultra-fast gas chromatography electronic nose, the rapid identification of odor difference markers of raw and bran-fried Zhiqiao (Aurantii Fructus) decoction pieces (RAF and BAF) was studied, and an effective and rapid identification method based on odor was proposed. Methods Through the establishment of Heracles NEO ultra-fast gas phase electronic nose detection method for RAF and BAF, combined with the Arochembase database, principal component analysis and discriminant factor analysis were used to process and analyze the odor chromatographic peaks of RAF and BAF. Results A rapid gas phase electronic nose analysis method for RAF and BAF was established. Through the analysis of the odor fingerprints of RAF and BAF, 11 odor characteristic components were matched. It was preliminarily speculated that D-limonene, β-myrcene and γ-terpinene may be the odor difference markers of RAF and BAF. Conclusion Heracles NEO ultra-fast gas phase electronic nose can better and quickly identify the odor characteristic components of RAF and BAF, and can be applied to the online quality monitoring of Chinese medicine processing, providing new ideas and methods for the rapid identification and quality control of different processed decoction pieces.

R283.6

国家重点研发计划项目（2018YFC1707000）