红芪是甘肃道地药材,现代药学研究表明红芪多糖是红芪的主要活性成分,是由五碳糖、六碳糖和其衍生物糖醇或糖酸构成的植物多糖,具有免疫调节、抗氧化、抗炎、抗肿瘤、机体保护、防治糖尿病及抗骨质疏松等药理作用。通过对红芪多糖的药理作用进行综述,阐明红芪多糖药理作用可能的机制,为红芪多糖的进一步研究及临床应用提供理论依据。

Hongqi (Hedysari Radix) is a genuine herbal medicine in Gansu Province, Modern pharmaceutical studies have shown that Hedysarum polybotrys polysaccharides (HPS) are the main active components of Hedysari Radix, which is a plant polysaccharide composed of five carbon sugars, six carbon sugars and their derivatives, sugar alcohols or acids. It has pharmacological effects such as immune regulation, anti-oxidation, anti-inflammatory, anti-tumor, body protection, prevention and treatment of diabetes and anti-osteoporosis. By summarizing the relevant literature of HPS, the pharmacological effects of HPS were reviewed to clarify the possible mechanism of pharmacological action of HPS. It is expected to provide theoretical basis and reference for further research and clinical application of HPS in various aspects.

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国家自然科学基金资助项目（81860683）；国家自然科学基金资助项目（82160730）；国家自然科学基金青年科学基金项目（82104345）；甘肃省教育厅双一流重大科研项目（GSSYLXM-05）；甘肃省科技计划项目（21YF5FA133）