疲劳是亚健康的典型表现，会导致身体发生一系列的生理变化。长期疲劳如不及时缓解，可诱发心血管功能障碍、精神障碍等严重病理反应。中药为防治疲劳、减缓继发性疾病提供了可靠的临床实践，具有抗疲劳作用的天然药物种类丰富，为开发利用新型抗疲劳药物提供崭新领域。通过对疲劳的认识、中药与天然药物防治疲劳的复杂机制进行综述，为揭示中药干预疲劳提供理论依据，也为开发具有抗疲劳潜力的新产品提供指导。

Fatigue is a typical manifestation of sub-health, which will lead to a series of physiological changes in the body. If long-term fatigue is not relieved in time, it can induce serious pathological reactions such as cardiovascular dysfunction and mental disorders. Traditional Chinese medicine provides reliable clinical practice for preventing fatigue and alleviating secondary diseases. Natural drugs with anti-fatigue effects are rich in variety and resources which provides a new field for the development of new anti-fatigue drugs. Through the review of the understanding of fatigue and the complex mechanism of traditional Chinese medicine and natural medicine in preventing fatigue, which provides theoretical basis for revealing the intervention of traditional Chinese medicine in fatigue, and also provides guidance for developing new products with anti-fatigue potential.

R282.710.5

国家中医药多学科交叉创新团队项目（中医药创新团队及人才支持计划）：中药研制与中药安全性创新团队（ZYYCXTD-D-202207）；江西中医药大学校级科技创新团队发展计划（CXTD22008）；江西省教育厅科技计划（GJJ218915，GJJ201206，GJJ201239）