[关键词]
[摘要]
功能性便秘是临床上常见的、多发病性消化系统疾病,严重影响人类身心健康。目前化学药治疗短期疗效较好,但是远期疗效欠佳,且常存在不良反应大、停药后易复发、长期服用产生依赖性等问题。功能性便秘病机为症多责之于脏腑气血阴阳不足,证属本虚标实。首荟通便胶囊根据此病机立意,养阴益气,补泻兼施,治疗功能性便秘效果显著。基于近年来首荟通便胶囊的研究进展,对首荟通便胶囊治疗功能性便秘的作用机制和临床疗效进行归纳总结,为临床合理应用首荟通便胶囊治疗功能性便秘提供理论依据和用药指导,同时也为今后研究首荟通便胶囊治疗功能性便秘的作用机制提供方向。
[Key word]
[Abstract]
Functional constipation is a digestive system disease with a high prevalence commonly encountered in clinical settings, which could seriously affect human physical and mental health. At present, the short-term efficacy of chemical drugs is well, but the long-term efficacy is poor. In addition, chemical drugs often have characteristics such as large side-effects, easy recurrence after drug withdrawal, drug dependence. The pathogenesis of functional constipation is mainly due to the deficiency of qi, blood, yin and yang of zang-fu. The disease pathogenesis is essential empty and out solid. Based on the pathogenesis, Shouhui Tongbian Capsules (首荟通便胶囊) could help supplementing qi and nourishing yin, and purgation and tonification in the treatment. Many studies have found that the curative effect of Shouhui Tongbian Capsules for functional constipation were remarkable. Based on research progress in recent years, the latest progress on mechanism and clinical effect of Shouhui Tongbian Capsules in treatment of functional constipation were summarized in this paper, in order to provide theoretical basis and medication guidance for more rational application of Shouhui Tongbian Capsules in treatment of functional constipation. It will also provide a direction for the future research on mechanism of Shouhui Tongbian Capsules in treatment of functional constipation.
[中图分类号]
R286.5
[基金项目]
国家自然科学基金面上项目(81773997);山东省重点研发计划项目(2017CXGC1301);济南市科技计划项目(202019132)