山鸡椒Litsea cubeba在民间有着悠久的药用历史，可用于治疗腹痛吐泻、风湿痹痛、跌打损伤及脑血栓等疾病，主要含有挥发油类、生物碱类、木脂素类、黄酮类等化学成分，具有抗炎、抗肿瘤、抗菌、抗氧化、镇痛等药理作用。系统总结了1980—2021年国内外有关山鸡椒化学成分、药理活性及临床应用的研究进展，为其进一步开发和应用提供参考依据。

Litsea cubeba has been historically used as a folk medicine to treat abdominalgia, vomiting and diarrhoea, rheumatic arthritis, traumatic injuries, and cerebral thrombosis. The plant mainly contains volatile oil, alkaloids, lignans, flavonoids and possesses a wide range of biological activities, such as anti-inflammatory, antitumor, antimicrobial, antitioxidant and analgesic activities. Research progress on chemical constituents, pharmacological activities and clinical applications of L. cubeba from 1980 to 2021 were reviewed in this paper, in order to provide a reference for further development and utilization of L. cubeba.

R282.710.85

广西中医药大学博士科研启动基金资助项目（2020BS017）