目的 对壳斗科锥属植物锥Castanopsis chinensis叶的化学成分进行研究。方法 采用80%甲醇室温浸提取、石油醚脱脂，水层部分采用Sephadex LH-20、Diaion HP20SS及Toyopearl HW-40F柱色谱等方法进行分离纯化，根据化合物NMR、MS数据以及与文献对比鉴定其结构。结果 从锥叶中分离鉴定了11个化合物，分别为4'-O-β-D-吡喃葡萄糖基-3',4',5'-三羟基苯基咖啡酸酯（1）、5-O-咖啡酰奎宁酸（2）、5-O-阿魏酰奎宁酸（3）、咖啡酸甲酯（4）、没食子酸（5）、脱氢双没食子酸（6）、(2'R)-phaselic acid（7）、山柰酚（8）、槲皮素（9）、山柰酚-3-O-α-L-鼠李糖苷（10）、槲皮素-3-O-α-L-鼠李糖苷（11）。结论 所有化合物均为首次从锥中分离得到，其中化合物1为新化合物，命名为锥苷A。

Objective To study the chemical constituents from the leaves of Castanopsis chinensis. Methods The leaves of C. chinensis were extracted with 80% CH₃OH and degreased by petroleum ether. The aqueous layer was isolated and purified by Sephadex-LH 20, Diaion HP20SS, Toyopearl HW-40F column chromatography. Their structures were identified by NMR, MS and literature comparison. Results Eleven compounds were isolated and identified as 4'-O-β-D-glucopyranosyl-3',4',5'-trihydroxybenzyl-caffeate (1), 5-O-caffeoylquinic acid (2), 5-O-feruloylquinic acid (3), caffeic acid methyl ester (4), gallic acid (5), dehydrodigallic acid (6), (2'R)-phaselic acid (7), kaempferol (8), quercetin (9), kaempferol-3-O-α-L-rhamnoside (10) and quercetin-3-O-α-L-rhamnoside (11). Conclusion All compounds are obtained from C. chinensis for the first time, and compound 1 is identified as a new phenol glucoside named chinensin A.

R284.1

国家自然科学基金项目（21562008）；广西科技基地和人才专项（桂科AD21075004）；广西科学院基本科研业务费项目（CQZ-C-1901）