[关键词]
[摘要]
香附作为我国传统中药材,用药历史悠久,临床应用广泛。现代研究表明香附的化学成分主要包括萜、黄酮、生物碱、糖、甾醇等类成分,具有抗肿瘤、抗抑郁、抗炎、抑菌、抗氧化和降血糖等药理作用。对香附化学成分和药理作用的研究进展进行综述,并对其质量标志物(quality marker,Q-Marker)进行预测分析,α-香附酮、香附烯酮、氧化石竹烯和木犀草素等化合物可作为香附的主要Q-Marker,为香附的进一步研究和应用提供依据。
[Key word]
[Abstract]
As a traditional Chinese medicine, Xiangfu (Cyperi Rhizoma) has a long history and is widely used in clinic. Modern research has shown that chemical components of Cyperi Rhizoma mainly include terpenes, flavonoids, alkaloids, sugars, sterols and so on, with the pharmacological effects such as anti-tumor, antidepressant, anti-inflammatory, antibacteriostatic, antioxidant and hypoglycemic. Research progress on chemical constituents and pharmacological effects of Cyperi Rhizoma were reviewed in this paper, and its quality markers (Q-markers) were predicted and analyzed. α-Cyperone, cyperenone, caryophyllene oxide, and luteolin can be used as the main Q-Markers of Cyperi Rhizoma, in order to provide basis for further research and application of Cyperi Rhizoma.
[中图分类号]
[基金项目]
中央引导地方科技发展资金项目(206Z2501G);河北省重点研发计划项目(20372502D)