山羊角为牛科动物山羊Capra hirus的角，具有清热、镇惊、明目、解毒之功，主要用于治疗小儿惊厥、高热神昏、青盲等疾病。系统梳理总结山羊角的本草记载与历史沿革、物质组成、药理活性、鉴定与质量评价方法、现代临床应用，深入挖掘了山羊角的药用资源价值，并进一步提出以类效替代原则开发珍稀动物药新资源药材的思路与建议，为实现珍稀濒危角类药材资源的补偿与供给、引导山羊产业加工过程巨量副产物的资源化利用、服务于中药资源产业的可持续发展及畜牧产业的提质增效提供科学依据。

Goat horn is the horn of Capra hirus, which have the functions of clearing heat, suppressing convulsions, improving eyesight, detoxifying, and can be used to improve infantile convulsion, fever and unconsciousness, green blind and other diseases. Herba records and historical evolution, substance composition, pharmacological activities, identification and quality evaluation methods, and modern clinical application were systematically reviewed in this paper. And then idea and proposal concerned further exploitation on medicinal value of goat horn, developing new resources of medicinal materials following the similar effect substitution principle were pointed out, in order to achieve the compensation and supply of rare and endangered animal horn derived traditional Chinese medicine, guide the resource utilization for side products of goat industry, and provide scientific basis for sustainable development of traditional Chinese medicine resource industry and improving quality and efficiency of animal husbandry industry.

R282.740.5

国家重点研发计划资助项目（2018YFC1706100）；国家自然科学基金面上项目（81973450）；中华中医药学会“青年人才托举工程”（QNRC2-C14）；江苏省高校“青蓝工程”中青年学术带头人；南京中医药大学中药学一流学科开放课题（2020YLXK009）