[关键词]
[摘要]
射干Belamcanda Chinensis是我国常用的中药材,资源丰富,分布较广,具有广阔的开发利用前景。射干中化学成分类型较为丰富,主要为黄酮类、三萜类、挥发油、甾体类等,一般认为异黄酮为其主要药效成分。在射干化学成分、药理作用综述的基础上,根据中药质量标志物(quality marker,Q-Marker)理论,从化学成分与传统功效、传统药性、可测成分、不同产地和采收时期、入血成分及不同配伍环境几方面对射干Q-Marker成分进行预测分析,发现以鸢尾苷、鸢尾黄素、野鸢尾黄素、白射干素、芒果苷表现最为显著,为明确射干Q-Marker和制定科学的质量标准提供理论基础。
[Key word]
[Abstract]
Belamcanda Chinensis is a commonly used Chinese medicinal material in China, which has abundant resources, wide distribution and broad prospects for development and utilization. The chemical compositions are rich in B. chinensis, including flavonoids, triterpenes, volatile oils, steroids.etc. Traditionally, isoflavones are considered to be the main medicinal ingredients. Based on the summarization of its chemical components and pharmacological effects, the Q-Markers of B. chinensis are predicted from the aspects of chemical components, traditional properties, detectable components, different producing areas, collecting periods, components entering blood and different compatibility environments. It was found that iris, iris flavin, wild kite flavin, eucalyptin and mangiferin were the most significant, which can provide basis for clarifying the Q-Markers and establishing scientific quality standards of B. chinensis.
[中图分类号]
R28
[基金项目]
国家重大新药创制专项(2019ZX09201005);国家自然科学基金青年科学基金项目(82003936);中医药国际合作专项(基地类项目)(0610-2140NF020630)