目的 通过Heracles Neo超快速气相电子鼻技术，建立广藿香饮片快速鉴别方法，建立专属性特征性强的广藿香饮片气味指纹图谱。方法 采用Heracles Neo超快速气相电子鼻对广藿香饮片及黑龙江、四川和湖南3个产地的藿香饮片样品进行气味分析，根据获取的气味色谱信息，结合Kovats保留指数及Arochembase数据库内容，通过建立的化学计量学模型实现广藿香饮片的快速鉴别，通过2个不同极性色谱柱，即MXT-5（低极性）和MXT-1701（中极性），对广藿香饮片真实气味进行气味指纹图谱的研究。结果 通过主成分分析（principal component analysis，PCA）、判别因子分析（discriminant factor analysis，DFA）、软独立建模分析（soft independent modeling of class analysis，SIMCA）3种化学计量学模型能够实现对广藿香饮片的快速鉴别，通过方法学考察得到2个不同极性色谱柱下专属性特征性强的广藿香饮片的气味指纹图谱。结论 所建立的广藿香饮片气味指纹图谱专属性强，可以根据所建立的气味指纹图谱对广藿香饮片进行快速鉴别，为中药材的真伪快速鉴别及中药饮片整体性质量的评价控制提供新技术和新方法。

Objective By Heracles Neo ultra-fast gas-phase electronic nose technology, a rapid identification method for Guanghuoxiang (Pogostemonis Herba, PH) was established, and the odor fingerprint of PH with strong specific characteristics was established. Methods Heracles Neo ultra-fast gas phase electronic nose was used to analyze the odor of PH and Huoxiang samples from Heilongjiang, Sichuan and Hunan province. According to the obtained odor chromatographic information, combined with the Kovats retention index and the Arochembase database, the rapid identification of Pogostemon cablin was obtained with established chemometric model. MXT-5 (low polarity) and MXT-1701 (medium polarity) were used to analyse the odor fingerprint of P. cablin. Results A rapid identification method for P. cablin was achieved by three chemometric PCA (principal component analysis), DFA (discriminant factor analysis) and SIMCA (soft independent modeling of class analysis). And the specific odor fingerprints of P. cablin by two different polarity chromatographic columns were obtained. Conclusion The established P. cablin scented fingerprints of decoction pieces were highly specific, and could be used to quickly identify P. cablin scented pieces based on the established odor fingerprints, providing new ways for the rapid identification of authenticity of Chinese medicinal materials.

R283.6

国家重点研发专项——中药饮片质量识别关键技术研究（2018YFC1707000）