[关键词]
[摘要]
目的 对生姜Zingiberis Rhizoma Recens的丙酮溶解部位进行化学成分研究。方法 综合应用多种色谱技术进行分离纯化,通过各种现代谱学技术对化合物进行结构鉴定。结果 从生姜水部位的丙酮溶解物中,分离得到8个化合物。分别鉴定为(1S,2R,4R)-1-甲基-1,2-二羟基-4-(2-羟基异丙基)-环己烷(1)、脱氢松香酸(2)、staphylionoside D(3)、12α-hydroxyabieta-7,13-abietadien-18-oic acid(4)、sachaloside VII(5)、1-(羟甲基)-5,5-二甲基双环[3.1.1]庚-2-烯-4-醇(6)、(E)-1,6,7-三羟基-3,7-二甲基-2-辛烯(7)、(2E,6E)-8-β-D-glucopyranosyloxy-2,6-dimethyl-2,6-octadienoic acid(8)。结论 化合物1为新化合物,命名为姜萜A,化合物2~5首次从生姜中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents of acetone extract from Shengjiang (Zingiberis Rhizoma Recens). Methods The chemical constituents of Zingiberis Rhizoma Recens were separated and purified by chromatographic methods and structurally elucidated by means of various spectroscopic techniques. Results A total of eight compounds were isolated from the acetone extract of Zingiberis Rhizoma Recens, and identified as (1S,2R,4R)-1-methyl-1,2-dihydroxy-4-(2-hydroxyisopropyl)- cyclohexane (1), dehydroabietic acid (2), staphylionoside D (3), 12α-hydroxyabieta-7,13-abietadien-18-oic acid (4), sachaloside VII (5), 1-(hydroxymethyl)-5,5-dimethylbicyclo[3.1.1]hept-2-en-4-ol (6), (E)-1,6,7-trihydroxy-3,7-dimethyl-2-octene (7), (2E,6E)-8-β- D-glucopyranosyloxy-2,6-dimethyl-2,6-octadienoic acid (8). Conclusion Compound 1 is a new compound, named ginger terpene A, and compounds 2-5 are isolated from Zingiberis Rhizoma Recens for the first time.
[中图分类号]
R284.1
[基金项目]
河南省自然科学基金面上项目(212300410368);河南省中医学科研究专项课题(20-21ZY1040)