从"扶正"和"祛邪"中药的角度出发，根据其主要药效成分及抗肿瘤作用机制，探讨中药"扶正"和"祛邪"与抗肿瘤作用的辨证关系。"扶正"使人体充满正气，外邪不能入侵，提高机体整体免疫力。"祛邪"消除侵入体内的病邪，如诱导肿瘤细胞的凋亡、抑制肿瘤细胞的增殖、抑制血管生成、诱导肿瘤细胞分化等；中药成分抗肿瘤作用机制的深入研究，为临床上灵活运用"扶正祛邪"治则提高疗效提供依据，为中医药治疗肿瘤和中药新药的研发提供了新思路。

The dialectical relationship between "strengthening vital energy" and "eliminating pathogenic factors" of traditional Chinese medicines and antitumor effects was discussed in this paper from the perspective of "eliminating pathogenic factors" and "strengthening vital energy" of traditional Chinese medicines, according to their main pharmacodynamic components and antitumor mechanism of action. "Fuzheng" is that the human body is full of vital qi, exogenous pathogens cannot invade, and improve the overall immunity of the body. "Quxie" eliminate the pathogenic factors invading the body, such as inducing the apoptosis of tumor cells, inhibiting the proliferation of tumor cells, inhibiting angiogenesis, and inducing the differentiation of tumor cells. The in-depth study of antitumor Chinese herbal components provides a basis for flexibly using the therapeutic principle of "Fuzheng Quxie" to improve the efficacy of clinical antitumor drugs, and provide a new idea for study of antitumor and research and development of new drugs of traditional Chinese medicine.

R282.710.5

黑龙江省自然科学基金资助项目（YQ2020H024）；黑龙江省博士后科研启动金资助项目（LBH-Q20027）；中央支持地方高校改革发展资金资助项目（2020YQ12）；哈尔滨商业大学“青年创新人才”支持计划项目（2019CX07）