徐长卿为萝摩科植物徐长卿Cynanchum paniculatum的干燥根和根茎，为我国传统中药，于《神农本草经》中列为上品。其化学成分多样，至今已发现挥发油类、C₂₁甾体类、多糖类、黄酮类成分等共计168余种。现代药理学研究表明，徐长卿具有广泛的镇痛、抗炎、抗病毒、神经保护等药理作用。主要对徐长卿的化学成分和药理作用的研究进展进行综述，并对其质量标志物（quality marker，Q-Marker）进行预测分析，丹皮酚和邻羟基苯乙酮可作为徐长卿的主要Q-Marker，以期为徐长卿进一步深入研究和临床应用提供参考。

Cynanchi Paniculati Radix et Rhizoma, the dry roots and rhizomes of Asclepiadaceae Cynanchum paniculatum, is a traditional Chinese medicine, which is listed as one of the highest grade herbs in “Shengnong’s Classic of Materia Medica”. Cynanchi Paniculati Radix et Rhizoma has a variety of chemical constituents, and 168 kinds of volatile oils, C₂₁ steroids, polysaccharides, flavonoids and other kinds of compounds have been found so far. Modern pharmacological studies have shown that it has a wide range of pharmacological effects, such as analgesia, anti-inflammation, antivirus, neuroprotection and so on. Research progress on chemical constituents and pharmacological effects of Cynanchi Paniculati Radix et Rhizoma were reviewed in this paper, and quality markers (Q-Markers) were predicted. Paeonol and 2'-hydroxyacetophenone can be used as the main Q-markers, which provide a reference for further research and clinical application.

R282.710.5

河北省自然科学基金资助项目（H2019423050）