[关键词]
[摘要]
罗汉果为葫芦科植物罗汉果Siraitia grosvenorii的干燥果实,是一种主产于广西的道地中药,也是药食两用药材。研究表明其含有罗汉果苷、黄酮类、多糖类、蛋白质及氨基酸、油脂类等多种化合物,且具有润肺止咳、润肠通便、调节糖脂代谢、保肝、抗肿瘤等多种药理活性。对罗汉果的化学成分和药理作用进行总结,并对其质量标志物(quality marker,Q-Marker)进行分析预测,为罗汉果进一步的开发利用提供科学依据。
[Key word]
[Abstract]
Siraitiae Fructus is the dried fruit of Siraitia grosvenorii, a Cucurbitaceae plant. It is a genuine traditional Chinese medicine mainly produced in Guangxi, also a medicinal and edible herb. Studies have shown that it contains a variety of compounds such as mogroside, flavonoids, polysaccharides, protein, and amino acids, oils, and so on. It has many pharmacological activities such as moistening lung and relieving cough, moistening intestines and defecating, regulating glycolipid metabolism, protecting liver, and anti-cancer. In this paper, the chemical constituents and pharmacological effects of Siraitiae Fructus are summarized, and the quality markers (Q-Marker) are analyzed and predicted to provide scientific basis for further development and utilization of Siraitiae Fructus.
[中图分类号]
R282.71
[基金项目]
中国-东盟传统药物研究国际合作联合实验室建设(二期)新中心建设项目(CICAR2017-Z1);广西重点实验室建设项目(19-050-39);广西中药药效研究重点实验室;广西科技计划项目(桂科AD19110165);广西科学研究与技术开发计划项目(桂科AD17195025);广西中医药大学2020年研究生教育创新计划项目(YCSZ202000)