甘草为临床常用配伍药材，在《神农本草经》中列为上品。甘草化学成分多样，至今已发现黄酮、三萜、香豆素、二苯乙烯等化合物共400余种。现代药理学研究表明，甘草具有广泛的抗肿瘤、抗炎、抗菌、抗病毒、神经保护、肝脏保护等药理作用。对甘草中新发现的化学成分、人工合成化学成分、炮制对化学成分的影响以及药理作用的国内外相关研究进展进行综述，以期为甘草的进一步开发利用提供参考。

Glycyrrhizae Radix et Rhizoma is a commonly used clinical compatible Chinese herbal medicine, which is listed as one of the highest grade herb in Shengnong’s Classic of Materia Medica. Glycyrrhizae Radix et Rhizoma has a variety of chemical constituents, and more than 400 kinds of flavonoids, triterpenoids, coumarins, stilbenoids and other kinds of compounds have been found so far. Modern pharmacological studies have shown that Glycyrrhizae Radix et Rhizoma has a wide range of anti-tumor, anti-inflammatory, antibacterial, antiviral, neuroprotective, liver protective, and other pharmacological effects. Related research progress on newly discovered chemical components, artificially modified chemical constituents, effects of processing on chemical components, and pharmacological effects at home and abroad in recent years are reviewed in this paper, which will provide references for the further development of Glycyrrhizae Radix et Rhizoma.

R282.71

河北省自然科学基金资助项目（H2019423050）；河北省中医药管理局科研计划项目（2017014）