目的 寻找中药水提液浓缩过程瞬时能耗计算简便方法。方法 以玉屏风散为模型药物，测定其水提液浓缩过程中多种溶液环境特征参数的动态变化数据，构建中药溶液环境特征参数白利度（简便、易测、准确）与浓缩能耗计算需要的相关参数的相关性模型。结果 白利度与固含率、密度、比热容、导热率等具有优越的线性相关，相关系数（R²）均高达0.99左右。结论 可通过测定白利度及构建与其他物理参数如比热容（C_p）、导热率（k_f）等关系模型，计算浓缩的动态能耗；为中药制药过程工程原理研究开辟新思路。

Objective To estimate the minimum energy requirement for the concentration of traditional Chinese medicine extract with ease. Method Yupingfeng Powder was chosen as the model formula. The selected key parameters were measured during the concentration process. Correlations between Brix and other key parameters were established. The significance of predicting the selected key parameters in this study were emphasized with the fundamental energy equations of the concentration processes. Result Brix had a strong correlation with the selected key parameters as the following:solid fractions, density, heat capacity, and thermal conductivity with a high value of R² greater than 0.99. Conclusion By establishing the appropriate relationships between the measured Brix and other key parameters such as heat capacity (C_p), and thermal conductivity (k_f), the dynamic energy consumption of the concentration processes of traditional Chinese medicine by conventional thermal process or novel membrane process, can be achieved. This will provide valuable insights into the fundamental study in pharmaceutical process engineering of traditional Chinese medicine.

R283.6

国家科技部重点研发计划“中医药现代化研究”重点专项（2019YFC1711300）；国家博士后科学基金第67批面上资助（2020M672575）；国家博士后科学基金第13批特别资助（2020T130130）