目的 研究鲜竹沥正丁醇部位的化学成分。方法 运用正相和反相硅胶、凝胶以及制备液相色谱方法进行分离纯化，并根据理化性质、波谱数据鉴定化合物的结构。结果 从鲜竹沥正丁醇部位分离得到16个化合物，分别鉴定为sachaliside 1（1）、（Z）-4-hydroxycinnamyl alcohol 4-O-β-D-glucopyranoside（2）、β-hydroxypropiovanillone-3-O-β-D-glucopyranoside（3）、dihydro-p-coumaryl alcohol γ-O-glucoside（4）、（+）-南烛木树脂酚-3α-O-β-D-吡喃葡萄糖苷（5）、tortoside B（6）、丁香脂素- 4-O-β-D-葡萄糖苷（7）、5，5'-二甲氧基落叶松树脂醇-4'-O-β-D-吡喃葡萄糖苷（8）、2，4，6-三甲氧基苯酚-1-O-β-D-吡喃葡萄糖（9）、苯甲醇-β-D-葡萄糖苷（10）、（1'R）-1'-（4-羟基-3，5-二甲氧基苯基）-1-丙醇-4-O-β-D-葡萄糖苷（11）、erythro-2，3-bis （4-hydroxy- 3-methoxyphenyl）-3-butoxypropan1-1-ol（12）、threo-2，3-bis（4-hydroxy-3-methoxyphenyl）-3-butoxypropan1-1-ol（13）、丁香脂素（14）、lirioresinol-A（15）、（E）-p-coumaryl alcohol γ-O-methyl ether（16）。结论 其中化合物2~4、6、10~13、15、16为首次从鲜竹沥中分离得到，并通过二维核磁谱补充了化合物4的碳谱数据。

Objective To study the n-butanol-soluble chemical constituents of Xianzhuli. Methods The chemical constituents were isolated by column chromatography on silica gel, ODS, Sephadex LH-20 and MPLC. Their chemical structures were elucidated on the basis of physical and chemical properties and spectral data. Results Sixteen compounds were isolated and identified as schaliside 1 (1), (Z)-4-hydroxycinnamyl alcohol 4-O-β-D-glucopyranoside (2), β-hydroxypropiovanillone-3-O-β-D-glucopyranoside (3), dihydro-p-coumaryl alcohol γ-O-glucoside (4), (+)-lyonirenisol-3α-O-β-D-glucopyranoside (5), tortoside B (6), syringaresinol 4-O-β-D-glucoside (7), 5,5'-dimethoxylariciresinol 4'-O-β-D-glucopyranoside (8), 2,4,6-trimethoxyphenol-1-O-β-D- glucopyranoside (9), benzylalcohol-β-D-glucopyranoside (10), (1'R)-1'-(4-hydroxy-3,5-dimethoxylphenyl) propan-1'-ol-4-O- β-D-glucopyranoside (11), erythro-2,3-bis(4-hydroxy-3-methoxyphenyl)-3-butoxypropan1-1-ol (12), threo-2,3-bis(4-hydroxy-3- methoxyphenyl)-3-butoxypropan1-1-ol (13), syringarenol (14), lirioresinol-A (15), and (E)-p-coumaryl alcohol γ-O-methyl ether (16). Conclusion Compounds 2-4, 6, 10-13, 15-16 are isolated from Xianzhuli for the first time. And the carbon spectrum data of compound 4 was supplemented.

R284.1

江西省重点研发计划一般项目（20171BBG70103）