3,4-裂环羽扇豆烷型三萜化合物及其生物活性研究进展

肖瑾，肖珊，罗姣，鲁曼霞，卢茂芳，刘向前; XIAO Jin; XIAO Shan; LUO Jiao; LU Man-xia; LU Mao-fang; LIU Xiang-qian

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2025年6月10日 21:08 星期二

首页 > 过刊浏览>2021年第52卷第6期 >2021,52(6):1834-1843. DOI:10.7501/j.issn.0253-2670.2021.06.033

3,4-裂环羽扇豆烷型三萜化合物及其生物活性研究进展

肖瑾
肖瑾
湖南中医药大学药学院, 湖南长沙 410208
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肖珊
肖珊
湖南中医药大学药学院, 湖南长沙 410208
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罗姣
罗姣
湖南中医药大学药学院, 湖南长沙 410208
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鲁曼霞
鲁曼霞
湖南中医药大学药学院, 湖南长沙 410208
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卢茂芳
卢茂芳
湖南中医药大学药学院, 湖南长沙 410208
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刘向前
刘向前
湖南中医药大学药学院, 湖南长沙 410208
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Email: lxq0001cn@163.com
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Advance in 3,4-seco-lupane type triterpenoids and their bioactivity

XIAO Jin
XIAO Jin
School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
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XIAO Shan
XIAO Shan
School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
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LUO Jiao
LUO Jiao
School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
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LU Man-xia
LU Man-xia
School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
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LU Mao-fang
LU Mao-fang
School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
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LIU Xiang-qian
LIU Xiang-qian
School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
Contact Author.
Email: lxq0001cn@163.com
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发布日期：2021-03-17

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[关键词]

3,4-裂环羽扇豆烷型三萜 ; 生物活性 ; 化学成分 ; 药理作用 ; 五加属 ; 抗炎 ; 抗肿瘤

[摘要]

3，4-裂环羽扇豆烷型三萜是五环三萜类化合物，在五加属植物中含量较为丰富。药理学研究表明该类成分具有广泛的生物活性，主要包括抗炎、抗菌、抗肿瘤等作用，具有潜在开发应用价值。通过查阅国内外相关文献报道，从化学结构特征、植物来源和生物活性等方面对天然来源的3，4-裂环羽扇豆烷型三萜类化合物的研究进展进行综述，以期为此类化合物的进一步研究及五加属植物药用资源的合理应用与开发提供参考依据。

[Key word]

3,4-seco-lupane type triterpenoids ; biological activity ; chemical component ; pharmacological activity ; Acanthopanax Miq. ; anti-inflammatory activity ; anti-cancer

[Abstract]

3,4-Seco-lupane type triterpenoids are pentacyclic triterpenoids, which are abundant in the plants of Acanthopanax genus. Pharmacological studies have shown that 3,4-seco-lupane type triterpenoids have a wide range of biological activities, such as anti-inflammatory, antibacterial, and anti-tumor activities. 3,4-seco-Lupane type triterpenoids have potential development and application value. By referring to relevant domestic and foreign literature reports, the research progress of 3,4-seco-lupane type triterpenoids is reviewed in terms of chemical structure, plant origin and biological activities. It provides a reference for further study of 3,4-seco-lupane type triterpenoids and the development of medicinal resources of Acanthopanax.

[中图分类号]

R284

[基金项目]

湖南省自然科学基金项目（2019JJ40223）；湖南中医药大学生物工程重点学科资助（校行科字[2018]3号）

引用本文 / Get Citation

肖瑾,肖珊,罗姣,鲁曼霞,卢茂芳,刘向前.3,4-裂环羽扇豆烷型三萜化合物及其生物活性研究进展[J].中草药,2021,52(6):1834-1843

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收稿日期: 2020-06-25

在线发布日期: 2021-03-17

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