煎煮时间对于保证中药汤剂临床疗效和中成药质量起着至关重要的作用，从古至今，中药汤剂煎煮终点的判断一直是困扰人们的技术难题。对中医药典籍《伤寒论》和《温病条辨》中汤剂的煎煮时间及其煎煮终点的判断经验进行了整理，发现其具有一定的规律，认为影响煎煮时间的因素主要有病证、方剂功效、药物药性、药材性状等；通过对其总结，并结合现代研究成果初步阐明传统中药汤剂煎煮终点的判断方法，以期能为中药汤剂煎煮时间及现代中药制剂的提取工艺寻求合理的科学依据，为保证中药汤剂临床疗效和中药制剂的质量提供理论基础。

The time of decocting plays an important role in ensuring the clinical efficacy of Chinese medicine decoction and the quality of traditional Chinese medicine, but from ancient times to the present, the judgment of the endpoint of Chinese medicine decoction has always been a technical problem. In this paper, the decocting time and the judgment methods in the Chinese medicine classics "Treatise on Febrile Diseases" and "Treatise on Differentiation and Treatment of Epidemic Febrile Disease" were analyzed. Certain laws of decocting time were found. It was demonstrated that the main factors affecting the decocting time were the disease, the efficacy of the prescriptions, the drug properties, and the characteristics of the medicine, etc. Combined with modern research results, the judgment method of the endpoint of traditional Chinese medicine decoction was expounded, hoping to seek a reasonable scientific basis for the boiling time of Chinese medicine decoction and the extraction process of modern Chinese medicine preparation, and provide a theoretical basis for ensuring the clinical efficacy of Chinese medicine decoction and the quality of Chinese medicine preparations.

R283.661

国家自然科学基金资助项目（81760711）；江西省自然科学基金资助项目（20192ACBL21033）