九蒸九晒黄精始创于中国古代，发扬于近现代；其炮制工艺历经生用→单蒸→重蒸→九蒸九晒的演变，可达到降低毒性、增强疗效、改变归经、利于贮存、消灭病菌等目的。黄精经九蒸九晒炮制后化学成分和药性药效均发生显著变化，广泛应用于医药品、保健品、食品、化妆品等领域。从九蒸九晒黄精炮制工艺的历史沿革、炮制机制、成分变化及临床应用等方面进行综述，为优化九蒸九晒黄精炮制工艺研究提供科学依据，为建立九蒸九晒黄精的质量标准控制体系奠定基础，也为遵古炮制研究提供参考依据。

The nine times steaming and nine times shining processing method of Polygonatum cyrtonema was originated in ancient China and developed in modern times. The historical evolution of its processing technology includes raw-used, single-steamed, re-steamed, nine times steaming and nine times shining. It can eliminate toxicity, enhance curative effect, change meridians, facilitate storage and eliminate bacteria and so on. After nine times steaming and nine times shining, the chemical composition and drug efficacy of P. cyrtonema changed significantly, and it is widely used in medicine, health care products, common food, cosmetics and other fields. The historical evolution, processing mechanism, composition change, and clinical application of P. cyrtonema are reviewed in this paper, which provide a scientific basis for optimizing the nine times steaming and nine times shining technology of P. cyrtonema, lay the foundation for establishing the quality control standard control system, and provide a reference for the study of observing the ancient processing.

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国家中医药管理局中药饮片标准化建设项目（ZYBZH-Y-SC-40）；云南大理药业股份有限公司课题（KJHX1603）；青阳县九华黄精康养产业研究院院士工作站项目资助（JHHJ-YSGZZ-19006，JHHJ-YSGZZ-19007）；温州医科大学人才科研启动项目（OTJ18037）