天麻Gastrodia elata是我国名贵中药，具有镇静安神、抗抑郁、抗焦虑、抗氧化、防病毒和抗肿瘤等多种药理学活性。主要对天麻抗抑郁作用的药效物质基础及抗抑郁机制研究进展进行归纳总结，并结合当前天麻抗抑郁在临床上的应用，为天麻的进一步研究和开发提供参考。

Gastrodia elata is a valuable traditional Chinese medicine with many pharmacological activities such as calming, anti-depression, anti-anxiety, anti-oxidation, anti-virus, and anti-tumor. In this paper, the research progress of the pharmacodynamic basis and antidepressant mechanism of anti-depression effect of G. elata is summarized. And combined with the current clinical application of G. elata anti-depression, a reference is provided for the further research and development of G. elata.

R282.71

国家自然科学基金资助项目（31660099）；国家自然科学基金资助项目（81473342）