目的 对红果樫木Dysoxylum binectariferum的叶部位进行化学成分研究。方法 综合应用多种色谱方法进行分离纯化，根据MS及核磁共振数据进行化合物结构鉴定。结果 从红果樫木叶的乙醇提取物中得到5个甾体类化合物，分别为豆甾-4（5）-烯-β，6β，22-三醇（1）、豆甾-5（6）-烯-3β，21，2-三醇（2）、2α，3β，4β-三羟基孕甾-16-酮（3）、2α，3β-二羟基-4β-乙酰氧基孕甾-16-酮（4）、2α，3β-二羟基孕甾-17（20）-烯-16-酮（5）。结论 化合物1为新化合物，命名为红果豆甾A。化合物2~5均首次从红果樫木中分离得到。

Objective To study the constituents of the leaves of Dysoxylum binectariferum. Methods The chemical constituents were isolated by various column chromatographic methods, and their structures were identified on the basis of MS and NMR spectral analysis. Results Five steroids were obtained and their structures were elucidated as stigmast-4(5)-en-3β,6β,22-triol (1), stigmast-5(6)-en-3β,21,22-triol (2), 2α,3β,4β-trihydroxypregnan-16-one (3), 2α,3β-dihydroxy-4β-acetoxypregnan-16-one (4) and 2α,3β-dihydroxypregnan-17(20)-en-16-one (5). Conclusion Compound 1 is identified as a new compound and named dybinstigm A. Compounds 2-5 are obtained from D. binectariferum for the first time.

R284.1

山东省自然科学基金资助项目（ZR2017BC061）；山东省科学院国际科技合作项目（2019GHPY01）