查阅本草和国内外相关文献，从商陆本草考证、真伪鉴定、炮制、成分与药理、临床研究及工农业资源开发等方面进行归纳总结。本草考证表明历代古籍有商陆或当陆或章陆等名称，其功效为外敷痈肿疮毒、内服利尿消肿，产地由西北向东南转移；商陆根具备同心环异常结构，有别于常见8种混伪品。商陆主要以醋制法进行减毒增效炮制。商陆主要有效成分为三萜皂苷、多糖和抗病毒蛋白（PAPs），具有利尿泻下、改善肾脏、肝脏、呼吸道炎症和神经性炎性疾病的作用，及抗菌、抗病毒、抗肿瘤等多种药理活性。临床主要用于组方治疗肝硬化腹水、肾病综合症等，外敷治疗便秘。商陆还在植物抗病、抗虫、环境修复等方面有重要应用价值，为该药用资源的合理开发和综合利用提供支持。

This paper summarizes the herbal textual research, authenticity identification, processing, composition and pharmacology, clinical studies, industry and agriculture resources development of Phytolaccae Radix based on the ancient herbology works and references. The herbal textual research showed that Phytolaccae Radix had different names like Shanglu or Danglu or Zhanglu. The effects are external application of carbuncle, swelling and sore toxin, internal administration of diuretic and hydroncus. The main producing area is transferred from northwest to southeast. The root has the abnormal structure of concentric ring, which is different from the eight kinds of common adulterants. It is mainly processed with vinegar to reduce toxicity and increase efficacy. Triterpenoid saponins, polysaccharides and pokeweed antiviral proteins (PAPs) are the main effective components of Phytolaccae Radix, which have the functions of diuresis and diarrhea, improving inflammation of kidney, liver, respiratory tract and neuroinflammatory diseases, as well as antibacterial, antiviral, antitumor and other pharmacological activities. It is mainly used for the treatment of cirrhosis ascites, nephrotic syndrome and external application for the treatment of constipation clinically. Phytolaccae Radix has important application value in plant disease resistance, insect resistance and environmental restoration. The clinical efficacy of Phytolaccae Radix is clear and it has made important progress in the research of components, pharmacology, industrial and agricultural resources development, which provides support for the rational development and comprehensive utilization of it.

R286.2

陕西中医药大学科研培育项目（2017PY32）；陕西中医药大学“秦药”品质评价及资源开发学科创新团队项目（2019-QN01）；陕西中医药大学“思邈青年学者”项目；陕西省高校青年杰出人才支持计划项目；咸阳市中青年科技领军人才项目；2019年医疗服务与保障能力提升补助资金项目（中医药事业传承与发展部分第四次全国中药资源普查项目）（财社【2019】39号）