[关键词]
[摘要]
目的 研究东亚小金发藓Pogonatum inflexum全草的化学成分。方法 采用硅胶、Sephadex LH-20柱色谱及RP-HPLC等方法进行分离纯化,并通过化合物理化性质与波谱数据分析比对的方法鉴定化合物的结构。结果 从东亚小金发藓中分离得到16个化合物,分别鉴定为苜蓿素(1)、次野鸢尾黄素(2)、3,5,4'-三羟基-7,3'-二甲氧基黄酮(3)、3,5,3'-三羟基-7,4'-二甲氧基二氢黄酮(4)、5,2'-二羟基-6,7-亚甲二氧基二氢黄酮(5)、5,2',3'-三羟基-6,7-亚甲二氧基二氢黄酮(6)、芹菜素(7)、山柰酚(8)、山柰素(9)、柚皮素(10)、槲皮素(11)、黄芩素(12)、木犀草素(13)、原儿茶醛(14)、4-羟基-3-甲氧基-苯甲醛(15)和2-羟基-5-(2-羟基-4-甲氧基苄基)-4-甲氧基-苯甲醛(16)。结论 所有化合物均首次从小金发藓属植物中分离得到,其中二氢黄酮类成分可能为该属植物的特征性成分。
[Key word]
[Abstract]
Objective To investigate the chemical constituents from Pogonatum inflexum. Methods The constituents were separated by column chromatographic methods of silica gel, Sephadex LH-20 column chromatography and liquid phase preparation, and the structure of the compounds was identified by comparing the physicochemical properties of the compounds with the spectral data. Results A total of 16 compounds were obtained from P. inflexum, which were identified as tricin (1), irisflorentin (2), 3,5,4'-trihydroxy-7,3'-dimethoxyflavone (3), 3,5,3'-trihydroxy-7,4'-dimethoxyflavanone (4), 5,2'-dihydroxy-6,7-methylenedioxy- flavanone (5), 5,2',3'-trihydroxy-6,7-methylenedioxyflavanone (6), apigenin (7), kaempferol (8), kaempferide (9), naringenin (10), quercetin (11), baicalein (12), luteolin (13), protocatechuic aldehyde (14), 4-hydroxy-3-methoxy-benzaldehyde (15), and 2-hydroxy-5-(2-hydroxy-4- methoxybenzyl)-4-methoxybenzaldehyde (16). Conclusion All compounds are isolated from the genus Pogonatum for the first time, among them, dihydroflavones may be the characteristic components of this genus.
[中图分类号]
R284.1
[基金项目]
国家自然科学基金资助项目(31070184);全国中药特色技术传承人才培训项目(T20194828003)