[关键词]
[摘要]
目的 研究黄果茄Solanum virginianum的化学成分。方法 通过硅胶柱色谱、Sephadex LH-20柱色谱及高效制备薄层对黄果茄中的化学成分进行分离纯化,根据理化性质和波谱数据对其化学结构进行阐明。结果 从黄果茄中发现并鉴定12个化合物,分别为5-羟基-8-甲氧基-6,7-亚甲二氧基黄酮(1)、7-羟基-6-甲氧基香豆素(2)、秦皮素(3)、5-羟基-6,7,3',4'-四甲氧基黄酮(4)、5-羟基-4',6,7-三甲氧基黄酮(5)、二氢阿魏酰酪胺(6)、反式-N-对羟基香豆酰酪胺(7)、5,3'-二羟基-6,7,4'-三甲氧基黄酮(8)、N-[2-(3,4-二羟基苯基)-2-羟乙基]-3-(4-甲氧基苯基)丙-2-烯酰胺(9)、N-反式香豆酰基章鱼胺(10)、5,7,4'-三羟基-6-甲氧基黄酮(11)、5,7,4'-三羟基-8-甲氧基黄酮(12)。结论 化合物1为新化合物,命名为黄果茄酮;化合物2~12为首次从黄果茄中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the fruits of Solanum virginianum. Methods By means of preparative HPTLC and column chromatography over silica gel and Sephadex LH-20, compounds were isolated and purified. Their structures were elucidated by physico-chemical properties and spectral analyses. Results Twelve compounds were obtained and identified as:5-hydroxy-8-methoxy-6,7-methylenedioxyflavone (1), 7-hydroxy-6-methoxy coumarin (2), fraxetin (3), 5-hydroxy- 6,7,3',4'-tetramethoxyflavone (4), 5-hydroxy-4',6,7-trimethoxyflavone (5), dihydro-N-feruloyltyramine (6), N-trans-coumaroyltyramine (7), 5,3'-dihydroxy-6,7,4'-tritermethoxyflavone (8), N-[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]-3-(4-methoxyphenyl)-prop-2-enamide (9), N-trans-coumaroyloctopamine (10), 5,7,4'-trihydroxy-6-methoxyflavone (11), and 5,7,4'-trihydroxy-8-methoxyflavone (12). Conclusion Compound 1 is a new flavonoid, named as solacarpumon, and compounds 2-12 are isolated from Solanum virginianum for the first time.
[中图分类号]
R284.1
[基金项目]
国家自然科学基金资助项目(21372189);山东省自然科学基金资助项目(ZR2019HM091)