目的 研究黄果茄Solanum virginianum的化学成分。方法 通过硅胶柱色谱、Sephadex LH-20柱色谱及高效制备薄层对黄果茄中的化学成分进行分离纯化，根据理化性质和波谱数据对其化学结构进行阐明。结果 从黄果茄中发现并鉴定12个化合物，分别为5-羟基-8-甲氧基-6，7-亚甲二氧基黄酮（1）、7-羟基-6-甲氧基香豆素（2）、秦皮素（3）、5-羟基-6，7，3'，4'-四甲氧基黄酮（4）、5-羟基-4'，6，7-三甲氧基黄酮（5）、二氢阿魏酰酪胺（6）、反式-N-对羟基香豆酰酪胺（7）、5，3'-二羟基-6，7，4'-三甲氧基黄酮（8）、N-[2-（3，4-二羟基苯基）-2-羟乙基]-3-（4-甲氧基苯基）丙-2-烯酰胺（9）、N-反式香豆酰基章鱼胺（10）、5，7，4'-三羟基-6-甲氧基黄酮（11）、5，7，4'-三羟基-8-甲氧基黄酮（12）。结论 化合物1为新化合物，命名为黄果茄酮；化合物2～12为首次从黄果茄中分离得到。

Objective To study the chemical constituents from the fruits of Solanum virginianum. Methods By means of preparative HPTLC and column chromatography over silica gel and Sephadex LH-20, compounds were isolated and purified. Their structures were elucidated by physico-chemical properties and spectral analyses. Results Twelve compounds were obtained and identified as:5-hydroxy-8-methoxy-6,7-methylenedioxyflavone (1), 7-hydroxy-6-methoxy coumarin (2), fraxetin (3), 5-hydroxy- 6,7,3',4'-tetramethoxyflavone (4), 5-hydroxy-4',6,7-trimethoxyflavone (5), dihydro-N-feruloyltyramine (6), N-trans-coumaroyltyramine (7), 5,3'-dihydroxy-6,7,4'-tritermethoxyflavone (8), N-[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]-3-(4-methoxyphenyl)-prop-2-enamide (9), N-trans-coumaroyloctopamine (10), 5,7,4'-trihydroxy-6-methoxyflavone (11), and 5,7,4'-trihydroxy-8-methoxyflavone (12). Conclusion Compound 1 is a new flavonoid, named as solacarpumon, and compounds 2-12 are isolated from Solanum virginianum for the first time.

R284.1

国家自然科学基金资助项目（21372189）；山东省自然科学基金资助项目（ZR2019HM091）