[关键词]
[摘要]
姜黄为我国传统中药,味辛、苦,性温,具有破血行气、通经止痛之功效,其用药历史悠久,最早收载于《新修本草》。对姜黄化学成分及主要药理活性进行总结,并基于传统性效及现代研究两方面对姜黄质量标志物进行预测分析。建议对姜黄的芳姜黄酮、α-姜黄酮、β-姜黄酮、姜黄素、去甲氧基姜黄素、双去甲氧基姜黄素及黄酮类等成分进行定性、定量分析,进一步开展其所含的萜类和甾醇类等成分化学物质组的深入研究,为明确姜黄的质量标志物和姜黄质量评价研究提供科学依据。
[Key word]
[Abstract]
Curcuma longa, a well-known traditional Chinese medicine, which is warm in nature, acrid and bitter in taste. It has the effects of supplementing qi and activating blood circulation, treating amenorrhea, and pain relief. It was first collected in the Annotation of Materia Medica with long medication history. In this paper, chemical composition and main pharmacological activities of C. longa were summarized, and the quality markers of C. longa were predicted and analyzed based on traditional efficacy and modern research. It is suggested that the identification and quantification of ar-turmerone, α-turmerone, β-turmerone, curcumin, demethoxycurcumin, bisdemethoxycurcumin, and flavonoids should be carried out and the further research of the chemical group of terpenoids and sterols from C. longa should be focused, which could provide scientific basis for clarifying the quality marker (Q-marker) and quality evaluation research of C. longa.
[中图分类号]
R286.2
[基金项目]
中国东盟传统药物研究国际合作联合实验室建设(桂科AD17195025);2017年广西中药药效研究重点实验室(17-259-20)