甘薯Ipomoea batatas是一种食药同源性植物，能够提供维生素、矿物质、碳水化合物、蛋白质、花青素、必需脂肪酸以及微量元素等多种营养成分，这些生物活性物质可从多个方面发挥抗肿瘤、调节免疫、保护肝脏、降血糖、调血脂、抗衰老、调节肠道、减肥、抗辐射、抗疲劳等广泛的药理作用和保健功效。《中药大辞典》《中华本草》中记载了甘薯具有“补虚益气，健脾强肾”的功效。近年来甘薯以其丰富的活性成分和功能特性成为多个学科领域的研究热点。从基础研究和临床研究2方面对甘薯的体内生物活性研究进展进行综述，为其进一步开发研究及综合利用提供参考。

Ipomoea batatas is a kind of both edible and medicinal plant, which provides a dietary source of vitamins, minerals, carbohydrates, proteins, anthocyanins, essential fatty acids, trace elements and other nutrients, and these active substances play a role in many pharmacological activities such as antitumor, immune regulation, hepatoprotective effect, hypoglycemic, hypolipidemic, anti-aging, intestinal regulation, anti-obesity, anti-radiation, anti-fatigue, etc, and promote health in many aspects. The Dictionary of Traditional Chinese Medicine and Chinese Materia Medica recorded that I. batatas have the characteristics of tonifying deficiency and replenishing qi, strengthening spleen and kidney. In recent years, it has become a research hotspot in multidisciplinary fields for its rich nutritional components and functional characteristics. In this paper, the research progress of biological activity of I. batatas in vivo was reviewed from aspects of basic and clinical researches, which may provide references for its further development, research and comprehensive utilization.

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黑龙江省自然科学基金资助项目（H2015088）；黑龙江省博士后特别资助项目（LBH-TZ0516）；中国博士后基金项目（2012M520761）；哈尔滨商业大学校级科研项目（18XN066）