[关键词]
[摘要]
茯苓Poria cocos是我国传统的药食同源中药材,具有利水渗湿、健脾、宁心等功效,在药品、食品及保健品中均有广泛应用。随着对茯苓的深入研究,其三萜类和多糖等主要化学成分、药理作用及应用开发研究备受关注。对茯苓的化学成分、药理作用进行系统综述,根据质量标志物的概念,从亲缘学及化学成分特有性、传统药效、传统药性、化学成分可测性、不同加工方法的影响等几个方面对茯苓质量标志物进行预测分析,为茯苓质量评价研究和产品开发提供科学依据。
[Key word]
[Abstract]
Poria cocos is a traditional Chinese medicine with homology of medicine and food in China. It has the effects of promoting diuresis, eliminating dampness, invigorating spleen, calming heart and so on. It is widely used in medicine, food and health care products. With the in-depth study of P. cocos, its triterpenes, polysaccharides and other major chemical components, as well as its wide range of pharmacological effects and application development research have attracted much attention. This paper systematically reviewed the chemical components and pharmacological effects of P. cocos, according to the concept of quality markers, the quality markers of P. cocos were predicted and analyzed from the aspects of the biosynthetic approach and specificity of chemical components, traditional medicinal efficacy, traditional medicinal properties, measurable components, different processing methods and so on, which provides a scientific basis for quality evaluation and product development of P. cocos.
[中图分类号]
R282
[基金项目]
国家重点研发计划项目(2017YFC1701600);国家重点研发计划项目(2017YFC1701601);国家重点研发计划项目(2017YFC1701602);国家重点研发计划项目(2017YFC1701603);国家重点研发计划项目(2017YFC1701605);安徽省科技重大专项(18030801131);安徽省教育厅高校科研创新平台团队项目(皖教秘科[2015]49号);安徽省中央引导地方科技发展专项资金(201907d07050002);安徽高校协同创新项目(GXXT-2019-043)