[关键词]
[摘要]
目的 研究万寿竹Disporum cantoniense的化学成分。方法 采用离子交换色谱、中压MCI柱色谱、ODS柱色谱、凝胶柱色谱、制备型和半制备型液相色谱等色谱技术进行分离,运用质谱、核磁等现代光谱技术鉴定化合物结构。结果 从万寿竹75%乙醇提取物中分离得到11个化合物,分别鉴定为2'-β-D-吡喃葡萄糖氧苄基-6-α-L-(4'-O-乙酰基)-吡喃鼠李糖氧基-2-羟基-3-甲氧基苯甲酸酯(1)、4',7-二羟基黄酮(2)、巴马汀(3)、异紫花前胡苷(4)、4'-O-β-D-葡萄糖基-5-O-甲维阿斯米醇(5)、紫花前胡苷元(6)、2-氨基吡啶(7)、远志寡糖酯A(8)、新野樱苷(9)、2″-鼠李糖基淫羊藿次苷II(10)、宝藿苷I(11)。结论 化合物1为新的化合物,命名为万寿竹酯苷;化合物2~11为首次从该属植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from Disporum cantoniense. Methods Separation was carried out by ion exchange chromatography, medium pressure MCI column chromatography, ODS column chromatography, gel column chromatography, preparative and semi preparative liquid chromatography; The structures of the compounds were identified by modern spectral techniques such as mass spectrometry and nuclear magnetic resonance. Results Eleven compounds were isolated and identified as 2'-β-D-glucopyranosyloxybenzyl-6-α-L-(4'-O-acetyl)-rhamnopyranosyloxy-2-hydroxy-3-methoxybenzoate (1), 4',7-dihydroxyflavone (2), palmatine (3), marmesinin (4), 4'-O-β-D-glucosyl-5-O-methylvisamminol (5), nodakenetin (6), 2-aminopyridine (7), tenuifoliside A (8), neosakuranin (9), 2″-O-rhamnosylicariside II (10) and baohuoside I (11). Conclusion Compound 1 is a new compound named disporumoside, compounds 2-11 are isolated from the genus of Disporum for the first time.
[中图分类号]
R284.1
[基金项目]
国家自然科学基金项目(81960701);江西省自然科学基金面上重点项目(20171ACB20039);江西省创新驱动“5511”工程项目优势科技创新团队(20165BCB19009);江西省百千万人才工程资助[赣人社字(2016)332号];南昌市优势科技创新团队[洪科字(2016)173号]