目的 研究三尖杉Cephalotaxus fortunei的化学成分。方法 采用薄层色谱、正相硅胶柱色谱、ODS反相柱色谱、HP20大孔树脂及Sephadex LH-20凝胶柱色谱、高效液相制备色谱等分离技术进行分离，运用¹H-NMR、¹³C-NMR、ESI-MS等多种波谱技术鉴定化合物的结构。结果 从三尖杉的乙醇提取物中分离得到了17个木脂素类化合物，分别鉴定为shonanin（1）、牛蒡子苷元（2）、α-铁杉脂素（3）、罗汉松脂酚（4）、去甲络石苷元（5）、表去甲络石苷元（6）、（7'S）-羟罗汉脂素（7）、（7'R）-羟罗汉脂素（8）、（7'S）-hydroxyarctigenin（9）、开环异落叶松树脂酚（10）、4，4'-di-O-methylcephafortinA（11）、5-（3''，4''-二甲氧基苯基）-3-羟基-3-（4'-羟基-3'-甲氧基苄基）-4-羟甲基二氢呋喃-2-酮（12）、cephafortin B（13）、二氢去氢二愈创木基醇（14）、7R，8S-4，7，9，9'-四羟基-3，3'-二甲氧基-8-O-4'-新木脂素（15）、7R，8R-4，7，9，9'-四羟基-3，3'-二甲氧基-8-O-4'-新木脂素（16）、threo-1，2-双（4-羟基-3-甲氧基苯基）-1，3-丙二醇（17）。结论 化合物3、6、10、17为首次从三尖杉属植物中分离得到，4、5、7～9、12、14为首次从三尖杉中分离得到。

Objective To study chemical constituents of Cephalotaxus fortunei. Methods The chemical constituents were separated and purified by preparative thin-layer chromatography, silica gel, ODS, HP20 macroporous resin and Sephadex LH-20 gel column chromatography, and semi-preparative HPLC. Their structures were determined by NMR and ESI-MS spectroscopic techniques. Results Seventeen lignans were isolated from the ethanol extracts of C. fortunei and their structures were identified as shonanin (1), arctigenin (2), α-conidendrin (3), matairesinol (4), nortrachelogenin (5), epinortrachelogenin (6), (7'S)-hydroxymatairesinol (7), (7'R)-hydroxymatairesanol (8), (7'S)-hydroxyarctigenin (9), secoisolariciresinol (10), 4,4'-di-O-methylcephafortin A (11), 5-(3'',4''-dimethoxyphenyl)-3-hydroxy-3-(4'-hydroxy-3'-methoxybenzyl)-4-hydroxymethyl-dihydrofuran-2-one (12), cephafortin B (13), dihydrodehydrodiconiferyl alcohol (14), 7R,8S-4,7,9,9'-tetrahydroxy-3,3'-dimethoxy-8-O-4'-neolignan (15), 7R,8R-4,7,9,9'-tetrahydroxy-3,3'-dimethoxy-8-O-4'-neolignan (16), and threo-1,2-bis-(4-hydroxy-3-methoxyphenyl)-1,3-propanediol (17). Conclusion Compounds 3, 6, 10 and 17 were isolated from genus Cephalotaxus for the first time, and compounds 4, 5, 7-9, 12 and 14 were isolated from C. fortunei for the first time.