目的 研究白及Bletilla striata中的糖苷类化学成分。方法 采用硅胶柱色谱、Sephadex LH-20和半制备液相色谱等现代分离方法和技术对其化学成分进行分离纯化，并根据理化性质和波谱数据进行结构鉴定。结果 从黔产白及95%乙醇提取物中分离得到了13个糖苷类化合物，分别鉴定为1-methyl-3-phenylpropyl-β-D-glucopyranoside（1）、1-（4-β-D-glucopyranosyl oxybenzyl）4-ethyl（2R）-2-isobutylmalate（2）、3'，5-dimethoxy-bibenzyl-3-O-β-D-glucopyranoside（3）、syringaresinol mono-β-D-glucoside（4）、4-O-（6'-O-glucosyl-p-coumaroyl）-4-hydroxybenzyl alcohol（5）、（4-hydroxyphenyl）methyl-β-D-glucopyranoside（6）、4-methylphenyl-β-D-glucopyranoside（7）、benzyl-β-D-glucopyranoside（8）、phenyl-β-D-glucopyranoside（9）、4-[（acetyloxy）methyl]phenyl-β-D-glucopyranoside（10）、batatasin III-3-O-glucoside（11）、天麻素（12）、4-（4-β-D-glucopyranosyl-oxybenzyl）-（2R）-2-isobutylmalate（13）。结论 化合物1是新天然产物，化合物3~6是首次从该植物中分离得到，化合物2、7~13为首次从白及属植物中分离得到。

Objective To study the glycoside chemical constituents of Bletilla striata grown in Guizhou Province. Methods The glycoside chemical constituents were separated and purified by silica gel column chromatography, MCI, gel column chromatography, medium pressure preparation, highperformance liquid chromatography and other modern separation methods. The structures were identified based on the spectral data. Results Thirteen glycosides were isolated from the 95% ethanol extracts:1-methyl-3-phenylpropyl-β-D-glucopyranoside (1), 1-(4-β-D-glucopyranosyl oxybenzyl) 4-ethyl (2R)-2-isobutylmalate (2), 3',5-dimethoxy-bibenzyl-3-O-β-D-glucopyranoside (3), syringaresinol mono-β-D-glucoside (4), 4-O-(6'-O-glucosyl-p-coumaroyl)-4-hydroxybenzyl alcohol (5), (4-hydroxyphenyl) methyl-β-D-glucopyranoside (6), 4-methylphenyl-β-D-glucopyranoside (7), benzyl-β-D-glucopyranoside (8), phenyl-β-D-glucopyranoside (9), 4-[(acetyloxy) methyl] phenyl-β-D-glucopyranoside (10), batatasin III-3-O-glucoside (11), gastrodin (12) and 4-(4-β-D-glucopyranosyl-oxybenzyl)-(2R)-2-isobutylmalate (13). Conclusion Compound 1 is a new natural product. Compounds 3-6 are isolated from this plant for the first time; Compounds 2, 7-13 are obtained from this genus for the first time.

国家自然科学基金资助项目（U1812403）；国家自然科学基金资助项目（81660580）；贵州省科技计划项目（QKHZC[2019]2753，QKHPTRC[2017]5737，QKHPTRC[2016]2832）；贵州省高层次创新人才培养计划项目（QKHRC[2016]4037）；中央引导地方科技发展专项（QKHZYD[2017]4001）；贵州省科技创新人才团队建设项目（QKHRCTD[2015]4026）；贵州省中药材产业体系建设项目（GZCYTX2015-0202）