目的 对柳叶五层龙Salacia cochinchinensis的化学成分进行研究。方法 利用硅胶柱色谱、MCI、Sephadex LH-20柱色谱和半制备型高效液相色谱等手段进行分离纯化，根据理化性质和波谱数据对化合物进行结构鉴定。结果 从柳叶五层龙90%乙醇提取物的石油醚萃取部分中分离得到8个化合物，分别鉴定为28-羟基大籽五层龙酸（1）、pachysandiol A（2）、pristimeronol（3）、28-hydroxy-friedelan-3-one-29-oic acid（4）、山柰酚-3-O-α-L-鼠李糖苷（5）、6，7-dimethoxy-4-hydroxyl-1-naphthoic acid（6）、蚱蜢酮（7）、3，4，5-三甲氧基苯甲酸甲酯（8）。结论 木栓烷型三萜为该属植物的主要成分之一，其中化合物1为新木栓烷型三萜，化合物2~8为首次从五层龙属植物中分离得到，所有化合物均为首次从该种植物中分离得到。

Objective To study the chemical constituents of Salacia cochinchinensis. Methods The isolates were obtained by silica gel, Sephadex LH-20, MCI column chromatography, as well as prep-HPLC methods. Their structures were indentified on the basis of NMR, MS analyses. Results Eight compounds were isolated from 90% ethanol extract of S. cochinchinensis. The structures were identified as 28-hydroxyl salaspermic acid (1), pachysandiol A (2), pristimeronol (3), 28-hydroxy-friedelan-3-one-29-oic acid (4), kaempferol-3-O-α-L-rhamnoside (5), 6,7-dimethoxy-4-hydroxyl-1-naphthoic acid (6), grasshopper ketone (7), 3,4,5-trimethoxyl benzoic acid methyl ester (8). Conclusion Compound 1 is a new friedelane-type triterpenoid. Compounds 2-8 were isolated from the Salacia genus for the first time.

国家自然科学基金资助项目（81560708）；云南省中青年学术技术带头人后备人才（2015HB050）