黄酮类化合物广泛存在于药用植物中，有着非常重要的药用价值。其药理作用主要表现在抗氧化、抗肿瘤、抗突变、抗炎、抗菌、抗衰老等方面。黄酮类化合物的提取是其应用于疾病治疗中的关键环节，近年来有许多新兴的中药提取方法广泛应用到了黄酮类化合物的提取当中。综述了黄酮类化合物提取新方法的应用概况，主要包括超临界流体萃取（SFE）、超声辅助提取（UAE）、微波辅助提取（MAE）、加压液体提取（PLE）、脉冲电场（PEF）辅助提取、酶辅助提取（EAE）、绿色溶剂提取、蒸汽爆破辅助提取、动态高压微流化（DHPM）辅助提取等，以期对黄酮类化合物的提取、开发和利用提供参考。

Flavonoids are widely found in medicinal plants, which have important medical properties. Flavonoids were proved to have many pharmacological activities, such as anti-oxidation, antitumor, antimutation, anti-inflammatory, antibacterial and anti-aging. The extraction of flavonoids is the crucial link in their clinical applications. In recent years, many emerging Chinese medicine extraction methods have also been widely used in the extraction of flavonoids. This paper reviews the current application of new methods for flavonoid extraction, in order to provide references for the extraction, development and utilization of flavonoids. These new extraction methods include supercritical fluid extraction (SFE), ultrasonic assisted extraction (UAE), microwave assisted extraction (MAE), pressurized liquid extraction (PLE), pulsed electric field (PEF) assisted extraction, enzyme assisted extraction (EAE), green solvent extraction, steam explosion assisted extraction, dynamic high pressure microfluidization (DHPM) assisted extraction, etc.

山东省中医药研究及产业化课题项目（XTCX2014C01-04）；2018年度山东中医药大学优秀青年科学基金（2018zk42）