[关键词]
[摘要]
目的 研究桑科榕属植物无花果Ficus carica果实的化学成分。方法 综合运用硅胶柱色谱、ODS柱色谱、Sephadex LH-20凝胶柱色谱以及制备型高效液相色谱等技术进行系统分离,根据化合物的理化性质及波谱数据鉴定化合物的化学结构。结果 从无花果果实的90%乙醇提取物中分离得到了16个化合物,分别鉴定为怀特酮(1)、甘草宁G(2)、4'-羟基-5,7-二甲氧基-6-(3-甲基-丁烯基)-异黄酮(3)、猫尾草异黄酮(4)、indicanine C(5)、木豆素(6)、美迪紫檀素(7)、高丽槐素(8)、4-羟基-3-甲氧基-8,9-亚甲二氧基紫檀烷(9)、3-羟基-9,10-二甲氧基紫檀烷(10)、松脂素(11)、杜仲树脂酚(12)、丁香树脂醇(13)、8-羟基松脂醇(14)、3-羟基-1-(4-羟基-3-甲氧基苯)-1-丙酮(15)和4-羟基-3-甲氧基苯乙醇(16)。结论 所有化合物均为首次从无花果中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the fruits of Ficus carica. Methods The chemical constituents of F. carica were separated and purified by silica gel, ODS, Sephadex LH-20 gel column chromatographies, and preparative HPLC. Their structures were identified by physicochemical properties, spectroscopic analysis, as well as comparisons with the data reported in literature. Results A total of 16 compounds were isolated from the 90% ethanol extract of the fruits of F. carica, which were identified as wighteone (1), gancaonin G (2), 4'-hydroxy-5,7-dimethoxy-6-(3-methyl-2-butenyl)-isoflavone (3), alpinumisoflavone (4), indicanine C (5), cajanin (6), medicarpin (7), maackiain (8), 4-hydroxy-3-methoxy-8,9-methylenedioxy pterocarpan (9), 3-hydroxy-8,9-dimethoxypterocarpan (10), pinoresinol (11), medioresinol (12), syringaresinol (13), 8-hydroxy pinoresinol (14), 3-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)-1-propanone (15), and 4-hydroxy-3-methoxyphenthyl alcohol (16).Conclusion All compounds are isolated from F. carica for the first time.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(31660097);国家自然科学基金资助项目(21662011);教育部创新团队项目(IRT-16R19)