前列腺癌发病率不断升高，且不可避免地会进展成为去势抵抗性前列腺癌，虽然治疗方式在不断更新，但预后仍不乐观。因中医药在增效减毒、提高生活质量、延长生存时间等方面的独特优势，其在去势抵抗性前列腺癌治疗中占据了非常重要的位置。对目前中医药治疗去势抵抗性前列腺癌的临床及基础研究进行归纳总结，为其临床治疗用药及基础研究提供借鉴。

The incidence of prostate cancer is increasing, and inevitably progresses to castration-resistant prostate cancer. Although the treatment is constantly updated, the prognosis is still not optimistic. Because of its unique advantages of effect-enhancing and toxicity-reducing, improving quality of life, and prolonging survival time, Chinese medicine has occupied a very important position in the treatment of castration resistant prostate cancer. This article summarizes the clinical and basic research of traditional Chinese medicine in the treatment of castration-resistant prostate cancer, and provides reference for clinical treatment and basic research.

天津市科技计划项目"天津市中医内科临床研究中心"（15ZXLCSY00020）；天津市科技计划项目"中医药多靶位效应对难治性激素非依赖性前列腺癌临床治疗方案的研究"（12ZCDZSY17000）；天津市卫生和计划生育委员会项目"益气解毒袪瘀方对激素非依赖性前列腺癌临床治疗方案的研究"（13081）