[关键词]
[摘要]
白细胞减少症是临床常见疾病,发病原因具有多样化,最常见为药物引起,且以抗肿瘤药物引起的白细胞减少症最为广泛。对于白细胞减少症的治疗,中药能够从多角度、多层面、多靶点发挥综合调控能力。驴胶补血颗粒作为补血益气中药,具有疗效好、使用方便,易被患者接受等特点,临床已有报道其在升高白细胞方面的应用。对驴胶补血颗粒全方、药对及单味药的升高白细胞的作用及机制进行综述,为扩大该药物的临床适应症及合理使用提供参考依据。
[Key word]
[Abstract]
Leukopenia is a common clinical disease with diverse pathogenesis. Leukopenia is mostly caused by drugs, especially anti-tumor drugs. For the treatment of leukopenia, Chinese materia medica can play an ability of comprehensive adjusting control from multi-angle, multi-dimension, and multi-target. As a good Chinese medicine for tonifying blood and replenishing qi, Lvjiao Buxue Granules has the advantages of high curative effect, convenient to use, and easy to be accepted by patients. It has been reported in clinical application for elevating leukocytes. This present review will focus on the research progress on the elevating leukocytes effects and mechanisms of Lvjiao Buxue Granules based on complicated Chinese herbal formula, herb-pair, and single herb, so as to provide a reference for expanding the clinical indications and rational use of the drug.
[中图分类号]
[基金项目]
中国博士后科学基金面上资助项目(2016M602414);山西省科技研究计划(201603D321077,201603D3113013,201601D011122,201701D22111344);山西省科技创新重点团队(201605D131045-18);山西省重点实验室(201605D111004);山西省研究生联合培养基地人才培养项目(2017JD02)