[关键词]
[摘要]
口腔崩解片是一种不需用水送服即可在口腔内迅速崩解的特殊片剂,具有崩解迅速、生物利用度高、服用方便等优势。中药口腔崩解片近年来发展迅速,为中药在急症治疗方面提供了新的思路。同时中药口腔崩解片面临着口感差、崩解迟缓、质量评价体系不完善等诸多问题。通过查阅近年来口腔崩解片的相关文献,从发展现状、制备工艺、主要问题、质量评价等方面进行综述,为中药口腔崩解片的深入研究提供参考和借鉴。
[Key word]
[Abstract]
Orally disintegrating tablets is a special tablet that can disintegrate rapidly in the mouth without taking with water. It has the advantages of rapid disintegration, high bioavailability, convenient utilization and so on. The orally disintegrating tablets of Chinese materia medica (CMM) have developed rapidly in recent years, which provides a new way of thinking for the treatment of acute diseases. At the same time, the orally disintegrating tablets of CMM are faced with many problems, such as poor taste, slow disintegration, imperfect quality evaluation system and so on. In this paper, we reviewed the development status, preparation technology, main problems, and quality evaluation from the related literatures of orally disintegrating tablets in recent years, so as to provide references for further research of orally disintegrating tablets of CMM.
[中图分类号]
[基金项目]