[关键词]
[摘要]
目的 研究离舌橐吾Ligularia veitchiana干燥根的化学成分。方法 采用溶剂法进行提取和萃取,采用硅胶柱色谱和Sephadex LH-20凝胶柱色谱等方法进行分离纯化,根据波谱数据进行结构鉴定。结果 从离舌橐吾干燥根中分离得到6个化合物,分别鉴定为离舌橐吾苷B(1)、齐墩果酸(2)、β-谷甾醇(3)、α-香树脂醇(4)、3-O-β-D-葡萄糖-α-香树脂醇苷(5)、β-胡萝卜苷(6)。结论 化合物1为1个新化合物,化合物4和5为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the roots of Ligularia veitchiana. Methods Some chromatographic methods were used to isolate the chemical constituents from the roots of L. veitchiana, their structures were elucidated on the basis of spectral data. Results Six compounds were isolated from roots of L. veitchiana and were identified as liguveitoside B (1), oleanolic acid (2), β-sitosterol (3), α-amyrin (4), α-amyrin-3-O-β-D-glucopyranoside (5), and β-daucosterol (6). Conclusion Compound 1 is a new compound, named liguveitoside B; Compounds 4 and 5 are isolated from L. veitchian for the first time.
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[基金项目]
河北省高等学校科学技术研究重点项目(ZD2018067);河北经贸大学校内科研基金项目(2016KYQ07);2017年博士科研启动经费资助(0112001049)