[关键词]
[摘要]
目的 研究鬼箭羽(卫矛Euonymus alatus带栓翅的枝条)中的化学成分。方法 采用多种柱色谱技术对鬼箭羽95%乙醇提取物进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果 从鬼箭羽提取物中分离得到了3个化合物,分别鉴定为(1S,2S,7E,11R,12S)-2,11-dihydroxy-1,12-oxidocembra-4(18),7(8)-diene(1)、hemerocallal A(2)、桦木酸甲酯(3)。结论 化合物1为新的西松烷型二萜,命名为鬼箭羽二萜A,化合物2和3为首次从鬼箭羽中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the twigs of Euonymus alatus. Methods Compounds were isolated and purified by a combination of various chromatographic techniques, and their structures were elucidated by physiochemical property and spectral analysis. Results Three compounds were obtained from 95% ethanol extract of the twigs of E. alatus and identified as (1S,2S,7E,11R,12S)-2,11-dihydroxy-1,12-oxidocembra-4(18),7(8)-diene (1), hemerocallal A (2), and betulinic acid methyl ester (3). Conclusion Compound 1 is a new cembranoid diterpene and named euonymuditerpene A, and compounds 2 and 3 are isolated from the twigs of Euonymus alatus for the first time.
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[基金项目]
北京市科委G20工程创新研究项目(Z181100002218029,Z171100001717009);国家自然科学基金项目(81872761,81473590,81473119)