目的 研究竹叶椒Zanthoxylum planispinum的化学成分。方法 采用硅胶柱色谱、Sephadex LH-20凝胶柱色谱、制备高效液相色谱等技术进行分离纯化，通过理化性质、核磁共振和质谱等光谱数据鉴定化合物的结构。结果 从竹叶椒的甲醇提取物中分离得到7个酰胺类化合物，分别鉴定为（2E，7E，9E）-N-isobutyl-6，11-dioxo-2，7，9-dodecatrienamide（1）、armatamide（2）、pellitorine（3）、lanyuamide I（4）、tetrahydro-bungeanool（5）、hydroxy-γ-isosanshool（6）、dihydrobungeanool（7）。结论 化合物1 为新的链状不饱和脂肪酸酰胺，命名为竹叶椒素，化合物2～7 均为首次从该植物中分离得到。

Objective To study the chemical constituents of Zanthoxylum planispinum. Methods The compounds were isolated and purified by repeated silica gel column chromatography, Sephadex LH-20 gel column chromatography, and preparative HPLC. Their chemical structures were identified on the basis of physico-chemical properties and spectral analysis. Results Seven amides were isolated and elucidated as (2E, 7E, 9E)-N-isobutyl-6,11-dioxo-2,7,9-dodecatrienamide (1), armatamide (2), pellitorine (3), lanyuamide I (4), tetrahydro-bungeanool (5), hydroxy-γ-isosanshool (6), and dihydrobungeanool (7). Conclusion Compound 1 is a new unsaturated alkylamide named planispinamide, and compounds 2-7 are obtained from this plant for the first time.

国家自然科学基金面上项目（31170701）；浙江省教育厅科研项目（Y201534531）