黄曲霉毒素是中药中较易产生的毒性极强的真菌毒素之一。建立黄曲霉毒素简单、快速、高通量、现场化的检测方法对实现中药黄曲霉毒素限量监控、保障中药安全性具有重要意义。酶联吸附免疫法（ELISA）和胶体金免疫色谱（GICA）技术为中药黄曲霉毒素的大批量快速检测和现场单个或少数样品即时检测提供了有效的技术手段。虽然现在已有较多关于此类检测方法的报道，但没有形成标准方法。对已报道的中药黄曲霉毒素检测方法进行综述，以期为形成方法标准提供参考。

Aflatoxins, one of highly toxic and carcinogenic mycotoxins, are widespread in nature including Chinese materia medica (CMM).A simple, fast, high-throughput and on-site detection method is urgent needed for the screening the aflatoxins content in CMM to guarantee its safety.Enzyme linked immunosorbent assay (ELISA) and gold immune chromatograohic assay (GICA) provide an effective technique for the high-throughput detection and on-site single or a few of samples real-time detection of aflatoxin.There have no standard methods though many immunoassays have been established in some studies.The objective of our work is to make a research on the progress of immunoassay for aflatoxin determination and to provide a reference for the standard establishment.

山东省自然科学基金资助项目（ZR2017BH010）