化感自毒作用是造成药用植物连作障碍的重要原因之一，会降低药用植物产量与品质。随着药用植物产业的发展，其连作障碍的问题日益突出，如何缓解药用植物连作障碍，是目前亟待解决的问题。对药用植物化感自毒作用的研究现状进行综述，阐述了药用植物化感自毒物质影响其生长发育的机制，即通过破坏细胞结构、干扰活性氧和激素的代谢、影响光合作用等方面抑制药用植物生长；分析了药用植物化感自毒作用与连作障碍的关系，综述了选育抗自毒药用植物品种、合理施肥、选用合理种植制度以及使用微生物制剂等方法在缓解药用植物连作障碍上的应用，并对该领域未来的研究方向进行展望，以期为药用植物生产提供借鉴。

Allelopathic autotoxicity is one of the important factors for the continuous cropping obstacle of medicinal plants, which will reduce the yield and quality. With the development of medicinal plants industry, the problem of continuous cropping obstacle is becoming more and more serious. How to alleviate the continuous cropping obstacle of medicinal plants needs to be solved urgently. This paper combines the research status of allelopathic autotoxicity in medicinal plants. On the one hand, expounds the mechanism that the allelochemicals of medicinal plants inhibit the growth and development of medicinal plants by damaging the cell structures, interfering with the metabolism of reactive oxygen species and phytohormones, affecting photosynthesis and so on. On the other hand, based on the analysis of the relationship between allelochemicals and continuous cropping obstacle of medicinal plants, this paper elucidated some methods to alleviate the continuous cropping obstacle of medicinal plants, such as breeding antiallelopathic autotoxicity medicinal plants varieties, rational fertilizing, selecting proper cropping system and using microbial agents, in order to provide reference for the production of medicinal plants.

四川省"育种攻关"项目（2011NZ0098-12-01）